Mast Cells – Rising Star Pediatrics

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Immune cells found in connective tissue and mucous membranes that play a central role in allergic reactions. When IgE antibodies on their surface bind to an allergen, mast cells release inflammatory mediators including histamine, leukotrienes, and prostaglandins.

Glossary: Histamine
A chemical released by mast cells during an allergic reaction, responsible for many common allergy symptoms.
Glossary: IgE (Immunoglobulin E) [IgE]
A type of antibody involved in allergic reactions and immunity against parasites.
Glossary: Leukotrienes
Inflammatory mediators released by mast cells and other immune cells, contributing to allergic reactions especially respiratory symptoms.
Glossary: Prostaglandins
Lipid compounds with hormone-like effects involved in inflammation and allergic responses.

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